{"id":6331,"date":"2026-09-08T10:00:00","date_gmt":"2026-09-08T08:00:00","guid":{"rendered":"https:\/\/www.casadicurapioxi.it\/?p=6331"},"modified":"2026-10-07T12:54:52","modified_gmt":"2026-10-07T10:54:52","slug":"lutezio-terapia-casa-di-cura-pio-xi","status":"publish","type":"post","link":"https:\/\/www.casadicurapioxi.it\/en\/2026\/09\/08\/lutezio-terapia-casa-di-cura-pio-xi\/","title":{"rendered":"Lutezio therapy at Casa di Cura Pio XI"},"content":{"rendered":"

Presso la Casa di Cura Pio XI \u00e8 attiva la Terapia con Lutezio-177<\/b>, una tecnologia medico-nucleare all’avanguardia che consente di colpire in modo selettivo e mirato le cellule tumorali, preservando i tessuti sani circostanti.<\/p>\n

How it works<\/h3>\n

Lutezio-177 is a radioactive isotope bound to a \u201cvehicle\u201d molecule that recognizes specific receptors on the surface of the tumor. Once attached to the cell, Lutezio releases radiation (beta particles) in a beam of only a few millimeters, destroying the DNA of the tumor.<\/p>\n

Main applications<\/h3>\n

Currently, this therapy is used primarily for:<\/p>\n

    \n
  • Neuroendocrine tumors (NETs):<\/strong> especially those gastro-enteric-pancreatic ones that express receptors for somatostatin (often treated with the drug Lutathera).<\/li>\n
  • Advanced Prostate Cancer:<\/strong> Used in metastatic cases resistant to castration (CRPC) that express the PSMA protein.<\/li>\n<\/ul>\n

    Procedure and administration<\/h3>\n
      \n
    • Modes:<\/strong> slow intravenous infusion, usually in about 20-30 minutes.<\/li>\n
    • Standard protocol:<\/strong> It often involves 4 spaced cycles of about 8 weeks apart from each other.<\/li>\n
    • Regime:<\/strong> It may require a brief stay in a \u201cprotected zone\u201d (about 3 days) for the management of radioactivity, although some centers of excellence are implementing day hospital protocols.<\/li>\n<\/ul>\n

      Common side effects<\/h3>\n

      Although it is generally well tolerated, the following may occur:<\/p>\n

        \n
      • Fatigue (asthenia) and nausea.<\/li>\n
      • Temporary reduction in white blood cells, red blood cells or platelets (anemia or leukopenia).<\/li>\n
      • Monitoring of renal function is necessary, as the drug is eliminated through the urine.<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"

        Lutezio-177 therapy is an advanced form of metabolic radiotherapy that selectively targets tumor cells while sparing healthy tissues.<\/p>","protected":false},"author":1,"featured_media":6338,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-6331","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/posts\/6331","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/comments?post=6331"}],"version-history":[{"count":3,"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/posts\/6331\/revisions"}],"predecessor-version":[{"id":6763,"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/posts\/6331\/revisions\/6763"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/media\/6338"}],"wp:attachment":[{"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/media?parent=6331"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/categories?post=6331"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.casadicurapioxi.it\/en\/wp-json\/wp\/v2\/tags?post=6331"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}